358 Histochemical Study of Allergic Inflammation in Conjunctiva From Ovalbumin Sensitized Rabbits after Ocular or Nasal Challenge
نویسندگان
چکیده
subjects gave their informed consent to obtain samples. Tear and Serum Samples were collected to determine cytokines IL2, IL-4, IL-5, IFN-g, TNF-a, IL-10 by cytometric bead arrays (CBA), following manufacturer’s instructions. Results: Patients showed lower significant levels of L-4 after 6 months of treatment, without changes in IL2, IL5, TNFa and IL10. Significant Clinical improvement was also observed since 3 months of treatment and was maintained until the end of 6 months. Conclusions: DLE could be an excellent therapeutic tool to improve the clinical outcome in ACNST patients; it is possible that clinical improvement could be Tear IL-4 dependent.
منابع مشابه
Local ocular immunotherapy for experimental allergic conjunctivitis.
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